IGF-1 LR3 (1mg)
$139.99
Description
Summary
IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is a synthetic analog of human IGF-1 designed to extend receptor interaction time and reduce binding to endogenous IGF-binding proteins (IGFBPs). This is achieved by a glutamic acid to arginine substitution at position 3 and the addition of a 13-amino-acid N‑terminal extension, resulting in a longer half-life and enhanced biological potency in experimental models. IGF-1 LR3 is commonly used in vitro and in vivo research to explore growth-factor signaling, protein synthesis, cellular proliferation, and tissue remodeling mechanisms across muscle, bone, and metabolic systems.
Clinical Data
Preclinical work indicates that IGF-1 and its analogs regulate glucose, fatty acid, and protein metabolism while influencing cartilage and bone turnover, steroid hormone activity, and muscle regeneration pathways via IGF-1 receptor (IGF1R) and insulin receptor signaling. The LR3 variant shows markedly reduced affinity for IGFBPs relative to native IGF-1, producing prolonged circulation time and sustained receptor engagement in experimental models. In laboratory settings, IGF-1 LR3 is typically supplied as a lyophilised powder and reconstituted for controlled studies of cell growth, differentiation, and anabolic signaling; dosing, route of administration, and study duration vary by protocol and remain an active area of investigation.
Choose Quantity
For research use only. Not for human consumption.
Frequently Asked Questions
Ideal storage can differ between different peptides. TransformPeptides preserves unreconstituted lyophilized peptides in a freezer (-20°C) for long-term stability. Refrigeration (1-8°C) is suitable for the storage of lyophilized peptides for at least 3 months after delivery. Reconstituted peptide storage conditions and stability/potency timeframes may differ. All Bacteriostatic and Sterile water should be kept in the fridge (1-8°C) to maintain sterility.
To calculate a desired dosage for any given peptide, please see our Peptide Calculator page. The tool calculates reconstitution volumes, concentrations, and dosage measurements with a visual syringe guide.
TransformPeptides currently offers a range of high-purity peptides which can be seen here on our website. TransformPharma however is a parent company of TransformPeptides which does offer other products. To view the catalogue of TransformPharma, please join our telegram channel.
Yes. We have a dedicated page on our website showcasing our certificates of analysis (COA) as well as providing guidance on how to verify third-party lab testing reports. These documents include purity testing results and other quality assurance data from accredited laboratories.
Currently TransformPeptides only ships to locations within Australia. Orders are shipped via AusPost from Canberra, ACT with an average 48-hour fulfilment time and full tracking included.