Cagrilintide (10mg)
$174.99$159.99
Description
Summary
Cagrilintide is a long-acting synthetic amylin analog engineered for extended receptor engagement and weekly administration in metabolic research. It selectively binds both amylin and calcitonin receptors, slowing gastric emptying, enhancing satiety signalling, and suppressing postprandial glucagon secretion. As a complementary agent to incretin-based therapies (GLP-1 agonists and GLP-1/GIP dual agonists), cagrilintide has attracted substantial research attention for its additive weight-loss effects when co-administered with semaglutide-class molecules (the investigational combination known as cagrisema). For research use only—not for human consumption.
Clinical Data
Phase 2 clinical studies of cagrilintide monotherapy in adults with obesity reported dose-dependent weight reductions of 6.0% to 10.8% over 26 weeks with a favourable tolerability profile. When combined with semaglutide 2.4mg, trial data show average weight losses of approximately 15–17% over 20 weeks — materially exceeding semaglutide monotherapy — suggesting strong synergy between amylin and GLP-1 pathways. Pharmacokinetic work indicates an extended half-life of roughly 159–195 hours, supporting once-weekly administration and steady receptor engagement. Mechanistic studies confirm that dual amylin/calcitonin receptor activity modulates appetite and energy expenditure independently of GLP-1 signalling. Common observations in clinical settings include transient gastrointestinal effects that typically subside with dose titration.
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For research use only. Not for human consumption.
Frequently Asked Questions
Ideal storage can differ between different peptides. TransformPeptides preserves unreconstituted lyophilized peptides in a freezer (-20°C) for long-term stability. Refrigeration (1-8°C) is suitable for the storage of lyophilized peptides for at least 3 months after delivery. Reconstituted peptide storage conditions and stability/potency timeframes may differ. All Bacteriostatic and Sterile water should be kept in the fridge (1-8°C) to maintain sterility.
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